The multi-omics signatures of telomere length in childhood

Findings of this multi-omics study suggested an intricate interplay between telomere length, metabolism and immune responses, providing valuable insights into the molecular underpinnings of the early-life biological aging.

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Publication Details

Journal
BMC Genomics
Published
2025-01-27
DOI
https://doi.org/10.1186/s12864-025-11209-5
Primary Topic
Telomeres, Telomerase, and Senescence
Type
article
Field-Weighted Citation Impact
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The multi-omics signatures of telomere length in childhood

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BMC Genomics
Telomeres, Telomerase, and Senescence
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The multi-omics signatures of telomere length in childhood

Dolors Pelegrí-Sisó, Congrong Wang, Rossella Alfano, Regina Gražulevičienė, Rémy Slama, Dries S. Martens, Eduard Sabidó, Geòrgia Escaramí, Hector C. Keun, Mariona Bustamante, Kristine B. Gützkow, Michelle Plusquin, Marina Vafeiadi, Martine Vrijheid, Ángel Carracedo, Johanna Lepeule, Tim S. Nawrot, Léa Maître, Rosemary McEachan, Augusto Anguita‐Ruiz, Juan R. González, Leda Chatzi, John Wright, Eva Borràs
article en

Abstract

Findings of this multi-omics study suggested an intricate interplay between telomere length, metabolism and immune responses, providing valuable insights into the molecular underpinnings of the early-life biological aging.

BMC GenomicsVol. 26(1)
University of Southern California (US), Centre National de la Recherche Scientifique (FR), Norwegian Institute of Public Health (NO), University of Crete (GR), Inserm (FR), Universitat Pompeu Fabra (ES), Vytautas Magnus University (LT), Universidade de Santiago de Compostela (ES), Instituto de Salud Carlos III (ES), Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition (ES), Centre for Biomedical Network Research on Rare Diseases (ES), Center for Research in Molecular Medicine and Chronic Diseases (ES), Centro de Investigación Biomédica en Red (ES), Centre for Genomic Regulation (ES), Barcelona Institute for Global Health (ES), Instituto de Investigación Sanitaria de Santiago (ES), Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (ES), Servicio Gallego de Salud (ES), Institut pour l'avancée des biosciences (FR), Bradford Teaching Hospitals NHS Foundation Trust (GB), Imperial College London (GB), Universitat de Barcelona (ES), Hasselt University (BE), Université Grenoble Alpes (FR), KU Leuven (BE)
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Telomeres, Telomerase, and Senescence
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