Efficacy, Safety, Pharmacokinetics, and Immunogenicity of <scp>ABBV</scp>‐154 in Adults With Glucocorticoid‐Dependent Polymyalgia Rheumatica: A Phase 2, Randomized, Double‐Blind, Placebo‐Controlled Trial
Treatment effects were observed for ABBV-154 cohorts compared with placebo for time to flare. ABBV-154 was generally well tolerated. Due to early study termination, results should be interpreted with caution.
Authors
- Robert Spiera (ORCID: https://orcid.org/0000-0003-2911-6800)
- J. Anderson (ORCID: https://orcid.org/0000-0002-0893-3900)
- Claire Owen (ORCID: https://orcid.org/0000-0002-2694-5411)
- Julie Parmentier (ORCID: https://orcid.org/0009-0002-9773-5670)
- Federico Díaz‐González (ORCID: https://orcid.org/0000-0002-4139-9295)
- Valérie Devauchelle‐Pensec (ORCID: https://orcid.org/0000-0003-0432-825X)
- Denise Kruzikas
- Frank Buttgereit (ORCID: https://orcid.org/0000-0003-2534-550X)
- Ronilda D’Cunha
- Edit Drescher
- Dilek Arikan
- Tsutomu Takeuchi (ORCID: https://orcid.org/0000-0003-1111-8218)
- Yang� Yang (ORCID: https://orcid.org/0000-0003-1222-1209)
- Weihan Zhao (ORCID: https://orcid.org/0000-0002-9316-8181)
- Karen Stellpflug
Institutions
- Hospital for Special Surgery (US)
- Inserm (FR)
- Universidad de La Laguna (ES)
- Tokyo Medical University (JP)
- The University of Melbourne (AU)
- Keio University (JP)
- Cornell University (US)
- Hospital Universitario de Canarias (ES)
- Austin Hospital (AU)
- AbbVie (United States) (US)
- Humboldt-Universität zu Berlin (DE)
- Toldy Ferenc Kórház (HU)
- Centre Hospitalier Régional Universitaire de Brest (FR)
- Jahn Ferenc Dél-Pesti Kórház és Rendelőintézet (HU)
- Austin Health (AU)
- Freie Universität Berlin (DE)
- Charité - Universitätsmedizin Berlin (DE)
- Saitama Medical University (JP)
Publication Details
- Journal
- Arthritis & Rheumatology
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1002/art.43129
- Citations
- 5
- Primary Topic
- Heparin-Induced Thrombocytopenia and Thrombosis
- Type
- article
- Field-Weighted Citation Impact
- 10.03