Identifying gait differences between Alzheimer's disease and dementia with Lewy bodies and their associations with regional amyloid deposition
Gait was more impaired in dementia than in cognitively unimpaired (CU) controls. Compared with Alzheimer's disease (AD), Dementia with Lewy bodies (DLB) had more impaired pace, variability, and postural control. Step length and double support (%) distinguished DLB and AD with moderate accuracy.
Authors
- Val J. Lowe (ORCID: https://orcid.org/0000-0002-5612-1667)
- Kaylena A. Ehgoetz Martens (ORCID: https://orcid.org/0000-0002-8488-2295)
- Clifford R. Jack (ORCID: https://orcid.org/0000-0001-7916-622X)
- Farwa Ali
- Hajr Hameed (ORCID: https://orcid.org/0000-0003-1783-9673)
- Julie A. Fields (ORCID: https://orcid.org/0000-0002-1282-9866)
- Erik K. St. Louis (ORCID: https://orcid.org/0000-0002-2833-8826)
- Kejal Kantarci
- Ronald Petersen (ORCID: https://orcid.org/0009-0006-8296-6416)
- Bradley F. Boeve
- Salma Elasfar (ORCID: https://orcid.org/0009-0001-0531-5234)
Institutions
- Mayo Clinic (US)
- University of Waterloo (CA)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1002/alz.14351
- Citations
- 4
- Primary Topic
- Balance, Gait, and Falls Prevention
- Type
- article
- Field-Weighted Citation Impact
- 19.04
Funders
- Parkinson Society Canada
- National Institutes of Health
- Canadian Institutes of Health Research
- Natural Sciences and Engineering Research Council of Canada