Analysis of the potential biological mechanisms of geniposide on renal fibrosis by network pharmacology and experimental verification
Geniposide can attenuate renal fibrosis by inhibiting the PI3K/AKT pathway, suggesting its potential as a therapeutic agent for renal fibrosis.
Authors
- Rui Shi
- Deguang Wang (ORCID: https://orcid.org/0000-0003-4936-8773)
- Mengqian Liu
- Xunliang Li (ORCID: https://orcid.org/0000-0001-9964-2078)
- Wenman Zhao (ORCID: https://orcid.org/0000-0001-9846-242X)
- Zhijuan Wang (ORCID: https://orcid.org/0000-0003-4027-3591)
Institutions
- Anhui Medical University (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- BMC Pharmacology and Toxicology
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1186/s40360-025-00855-w
- Citations
- 2
- Primary Topic
- Saffron Plant Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- Anhui Medical University