WCN25-3811 PROGRESSION OF ANTICOAGULANT-RELATED NEPHROPATHY AFTER ANTICOAGULANT THERAPY

Anticoagulant-related nephropathy (ARN) is a recently discovered cause of AKI and possibly, progressive CKD as well. It occurs in patients receiving oral anticoagulant therapy, namely warfarin or a novel oral anticoagulant (NOAC). Many multi-center studies indicate that ARN occurs in up to 30 % of patients exposed to supratherapeutic INR when treated with vitamin K antagonists but little is known about ARN in direct oral anticoagulants. Our aim was to determine the incidence of ARN in patients with atrial fibrillation initiating (AF) oral anticoagulant treatment.