Multi-institutional evaluation comparing guidance from International Ki67 Working Group vs National Health Commission of China on immunohistochemistry-based Ki67 assessment alongside the Quantitative Dot Blot method
The IKWG recommendation was harder to achieve categorized agreement among pathologists than the NHCC recommendation, yet it led to the best agreement with the QDB to define the low-risk group. The QDB method offers significantly improved consistency compared to the current IHC-based Ki67 assessment.
Authors
- Zhiqiang Lang
- Bing Xiang Yang (ORCID: https://orcid.org/0000-0002-0227-4342)
- Yuhuan Wang (ORCID: https://orcid.org/0000-0001-6861-6205)
- Meiren Li
- Jiu Wang (ORCID: https://orcid.org/0009-0005-8594-3706)
- Hengming Zhang (ORCID: https://orcid.org/0000-0003-4225-1265)
- Zihan Zhu (ORCID: https://orcid.org/0000-0001-8273-8575)
- Zilan Zhang (ORCID: https://orcid.org/0000-0002-3553-2512)
- Jiarui Zou
- Yanqing Kong
- Guohua Yu (ORCID: https://orcid.org/0000-0002-3260-3178)
- Qinghua Cao (ORCID: https://orcid.org/0000-0002-1405-040X)
- Guihong Dai
- Yan Shen Peng (ORCID: https://orcid.org/0000-0001-5765-6260)
- Junmei Hao
- Yang Lin (ORCID: https://orcid.org/0009-0000-2552-6840)
- Chao Liu (ORCID: https://orcid.org/0000-0002-8844-0697)
- Cuiping Zhang (ORCID: https://orcid.org/0000-0002-5733-4672)
- Chunhui Liu (ORCID: https://orcid.org/0000-0002-3105-0006)
- Bichen Xie
- Xue Gong
- Hai-Yan Shi
- Jinyan Jiang (ORCID: https://orcid.org/0000-0001-6963-7200)
- Yin Wang
- Luting Zhou (ORCID: https://orcid.org/0000-0001-6083-796X)
- P H Fan
- Chenjia Lu
Institutions
- Qingdao University (CN)
- Jiangnan University (CN)
- Jiujiang University (CN)
- Binzhou Medical University (CN)
- Shandong University of Aeronautics (CN)
- Nantong University (CN)
- Ruijin Hospital (CN)
- Yuhuangding Hospital (CN)
- Soochow University (CN)
- Qinghai University Affiliated Hospital (CN)
- Integrated Chinese Medicine (China) (HK)
- Shenzhen Maternity and Child Healthcare Hospital (CN)
- ShenZhen People’s Hospital (CN)
- Weifang People's Hospital (CN)
- Wuxi Fourth People's Hospital (CN)
- People's Hospital of Xinjiang Uygur Autonomous Region (CN)
- The Affiliated Taizhou People's Hospital of Nanjing Medical University (CN)
- Henan Provincial People's Hospital (CN)
- Northern Jiangsu People's Hospital (CN)
- Guangdong Academy of Medical Sciences (CN)
- Hangzhou Red Cross Hospital (CN)
- Chenzhou First People's Hospital (CN)
- Guangdong Provincial People's Hospital (CN)
- Southern Medical University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-01-27
- DOI
- https://doi.org/10.3389/fonc.2024.1510273
- Citations
- 1
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Binzhou Medical University