Immunogenicity of SARS-CoV-2 Vaccination Schedules Including a Booster Dose in Patients with Systemic Lupus Erythematosus: Data from a Prospective Multicenter Study
In patients with SLE, SARS-CoV-2 vaccines are immunogenic, inducing a robust humoral response. No severe outcomes associated with death or hospitalization were found in the evaluated patient sample. Complete vaccination schedules including a booster dose induced higher humoral responses than incomplete schedules, especially in patients initially immunized with an inactivated virus vaccine schedule and those with a suboptimal humoral response.
Authors
- Viviane Angelina de Souza (ORCID: https://orcid.org/0000-0001-6386-3776)
- Rodrigo Cutrim Gaudio (ORCID: https://orcid.org/0000-0003-4895-1537)
- Erika Biegelmeyer (ORCID: https://orcid.org/0000-0003-4978-040X)
- Bruna Guimarães Dutra (ORCID: https://orcid.org/0000-0002-6464-3035)
- Vanessa Hax (ORCID: https://orcid.org/0000-0003-3240-7174)
- Jozélia Rêgo (ORCID: https://orcid.org/0000-0002-8935-1506)
- Natália Sarzi Sartori (ORCID: https://orcid.org/0000-0002-4316-0771)
- Renata Henriques de Azevedo
- Emília Inoue Sato (ORCID: https://orcid.org/0000-0001-8540-014X)
- Gilda Aparecida Ferreira (ORCID: https://orcid.org/0000-0002-1352-7261)
- Alexandre Wagner Silva de Souza (ORCID: https://orcid.org/0000-0001-7681-6215)
- Valderílio Feijó Azevedo (ORCID: https://orcid.org/0000-0002-2346-388X)
- Valéria Valim (ORCID: https://orcid.org/0000-0002-0625-1308)
- Vanessa Peruhype-Magalhães
- Vítor Alves Cruz (ORCID: https://orcid.org/0000-0002-3073-2929)
- Cristiane Kayser (ORCID: https://orcid.org/0000-0003-0543-5305)
- Marcos Mavignier Sousa Dias
- Ketty Lysie Libardi Lira Machado (ORCID: https://orcid.org/0000-0003-2545-6795)
- Paula dos Santos Athayde
- Luiza Lorenzoni Grillo
- J. Rodrigues (ORCID: https://orcid.org/0000-0001-9087-1771)
- Mariana Freitas de Aguiar (ORCID: https://orcid.org/0000-0002-8876-3226)
- Sérgio Henrique Oliveira dos Santos (ORCID: https://orcid.org/0000-0003-0129-0276)
- Camila Maria Paiva França Telles (ORCID: https://orcid.org/0000-0001-9168-9816)
- Victória Dornelas Paz Carvalho
- Vanessa de Oliveira Magalhães (ORCID: https://orcid.org/0000-0001-8662-4786)
- Gecilmara Salviato Pileggi (ORCID: https://orcid.org/0000-0003-0054-7754)
- Priscila Dias Cardoso Ribeiro (ORCID: https://orcid.org/0000-0003-2598-810X)
- Odirlei André Monticielo (ORCID: https://orcid.org/0000-0003-0720-2097)
- Samira Tatiyama Miyamoto (ORCID: https://orcid.org/0000-0003-0609-4063)
- Helena da Silva Corona (ORCID: https://orcid.org/0000-0002-7271-3435)
- Charlles Heldan de Moura Castro (ORCID: https://orcid.org/0000-0001-9144-996X)
- Valéria Bezerra da Silva (ORCID: https://orcid.org/0000-0002-9006-6139)
- Maria da Penha Gomes Gouvea (ORCID: https://orcid.org/0000-0003-2264-327X)
- Adriana María Kakehasi (ORCID: https://orcid.org/0000-0001-9411-7493)
- Flávia Maria Matos Melo Campos Peixoto
- Ana Paula Neves Burian (ORCID: https://orcid.org/0000-0002-5056-5523)
- Samuel Elias Basualto Dias (ORCID: https://orcid.org/0000-0001-6148-1491)
- Adah Sophia Rodrigues Vieira (ORCID: https://orcid.org/0000-0002-8090-9606)
- Andrese Aline Gasparin (ORCID: https://orcid.org/0000-0001-7786-9562)
- Marcelo M. Pinheiro (ORCID: https://orcid.org/0000-0002-1896-8322)
- Sandra Lúcia Euzébio Ribeiro (ORCID: https://orcid.org/0000-0002-4777-8659)
- Rodrigo Poubel Vieira de Rezende (ORCID: https://orcid.org/0000-0002-1623-259X)
- Ana Karla Guedes de Melo (ORCID: https://orcid.org/0000-0002-4809-9965)
- Juliana Bühring (ORCID: https://orcid.org/0000-0002-9944-7229)
- Filipe Faé
- Ricardo Machado Xavier (ORCID: https://orcid.org/0000-0001-6570-4533)
- Edgard Torres dos Reis-Neto (ORCID: https://orcid.org/0000-0003-0657-4825)
- Rejane Maria Rodrigues de Abreu Vieira (ORCID: https://orcid.org/0000-0003-4475-6064)
- Kátia Lino (ORCID: https://orcid.org/0000-0002-6134-8495)
- F. Z. Pretti
- Clara Pinheiro Martins (ORCID: https://orcid.org/0000-0003-2131-7341)
- Anna Carolina Faria Moreira Gomes Tavares (ORCID: https://orcid.org/0000-0002-1920-1115)
- Olindo Assis Martins-Filho
- Vasco Silva
- Andréa Teixeira-Carvalho
- Sabrina de Souza Ramos (ORCID: https://orcid.org/0000-0002-5330-8530)
- Karina Rosemarie Lallemand Tapia (ORCID: https://orcid.org/0000-0003-2033-9557)
- Anna Carolina Simões Moulin
- Yasmin Gurtler Pinheiro de Oliveira (ORCID: https://orcid.org/0000-0002-2049-5368)
Institutions
- Universidade Federal de Juiz de Fora (BR)
- Universidade Federal de Minas Gerais (BR)
- Universidade Federal do Rio Grande do Sul (BR)
- Universidade Federal Fluminense (BR)
- Universidade Federal da Paraíba (BR)
- Universidade de Fortaleza (BR)
- Hospital de Clínicas de Porto Alegre (BR)
- Hospital Universitário Lauro Wanderley (BR)
- Instituto de Saúde (BR)
- Hospital das Clínicas da Universidade Federal de Minas Gerais (BR)
- Secretaria da Saúde (BR)
- Universidade Federal do Espírito Santo (BR)
- Fundação Oswaldo Cruz (BR)
- Universidade Federal do Amazonas (BR)
- Universidade Federal de Goiás (BR)
- Universidade Federal de São Paulo (BR)
Publication Details
- Journal
- Vaccines
- Published
- 2025-01-27
- DOI
- https://doi.org/10.3390/vaccines13020127
- Citations
- 3
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 4.19
Funders
- Fundação Oswaldo Cruz