WCN25-4245 A CASE SERIES OF CONCURRENT IGA NEPHROPATHY AND ANTI- GBM DISEASE

IgA nephropathy is the most prevalent pattern of glomerular disease characterised by mesangial deposition of IgA +/- C3 deposition. Anti - glomerular basement membrane (GBM) disease is a rare autoimmune disorder with renal biopsy showing linear IgG staining along GBM accompanied by crescentric glomerulonephritis. Anti-GBM antibody is detected in about 95% patients. Though sporadic cases have been reported, it is extremely rare to find the two pathologies to coexist. The authors report 5 cases of this dual pathology association that illustrates the difficulty in diagnosing and managing such patients.