WCN25-3939 CLINICOPATHOLOGICAL PROFILE AND OUTCOMES IN PATIENTS WITH ACUTE INTERSTITIAL NEPHRITIS - A RETROSPECTIVE STUDY FROM A TERTIARY CARE CENTER IN SOUTH INDIA

All patients were treated with doxycycline and meropenem for ten days.The patient with crescentic GN was pulsed followed by oral steroids.Follow up and outcome -Three patient recovered AKI and four discharged on RRT.Whereas two died.One patient with crescents and AKI remained on RRT at one month.The patient with crescentic glomerulonephritis succumbed to pulmonary infection.Conclusions: Conclusion: AKI in leptospirosis due to acute interstitial nephritis has good outcome.Various autoimmune manifestations may be associated i.e.GBS, reactive arthritis, thrombocytopenia.Autoimmune biomarkers like P and C ANCA and Anti GBM may also be associated.The role of auto immune antibodies need to be explored further in pathogenesis of Leptospira AKI.I have no potential conflict of interest to disclose.I did not use generative AI and AI-assisted technologies in the writing process.