<i>Ide</i> Copy Number Variant Does Not Influence Stroke Severity in 2 C57BL/6J Mouse Models nor in Humans: An Exploratory Study
<i>Ide</i> CNV and loss of function variants are rare, do not crucially influence PcomA variability in C57BL/6J inbred mice, and do not cause a vascular phenotype in humans.
Authors
- Matthias Endres (ORCID: https://orcid.org/0000-0001-6520-3720)
- Katarzyna Winek (ORCID: https://orcid.org/0000-0003-3085-9054)
- Sonja Blumenau (ORCID: https://orcid.org/0000-0002-6606-3800)
- Rita Guerreiro (ORCID: https://orcid.org/0000-0001-5879-3486)
- Clarissa Rocca (ORCID: https://orcid.org/0000-0003-3233-5529)
- Celeste Sassi (ORCID: https://orcid.org/0000-0002-2837-1765)
- Ulrich Dirnagl (ORCID: https://orcid.org/0000-0003-0755-6119)
- Susanne G. Mueller (ORCID: https://orcid.org/0000-0002-5053-2211)
- Marco Foddis (ORCID: https://orcid.org/0000-0003-3354-6790)
- Dieter Beule (ORCID: https://orcid.org/0000-0002-3284-0632)
- Andreas Meisel (ORCID: https://orcid.org/0000-0001-7233-5342)
- José Brás (ORCID: https://orcid.org/0000-0001-8186-0333)
- Clemens Messerschmidt (ORCID: https://orcid.org/0000-0001-8632-656X)
- Arianna Tucci (ORCID: https://orcid.org/0000-0001-5644-0070)
- Alistair T. Pagnamenta
Institutions
- Van Andel Institute (US)
- Centre for Human Genetics (GB)
- Queen Mary University of London (GB)
- Humboldt-Universität zu Berlin (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- William Harvey Research Institute (GB)
- University College London (GB)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Stroke
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1161/strokeaha.124.049575
- Primary Topic
- Congenital heart defects research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Wellcome Trust
- Cancer Research UK
- National Institute for Health and Care Research
- Deutsche Forschungsgemeinschaft
- Fondation Leducq
- Bundesministerium für Bildung und Forschung
- Deutsches Zentrum für Neurodegenerative Erkrankungen
- Medical Research Council