WCN25-1933 WHEN THE SPIKES ARE NOT MEMBRANOUS: AN UNUSUAL PRESENTATION OF FIBRILLARY GLOMERULONEPHRITIS

eGFR over time were substantially lower in pts with CR or UPE <0.5 g/ d vs those who did not achieve these targets.Conclusions: In IgAN, achievement of low proteinuria is strongly predictive of better long-term kidney function.eGFR preservation was more evident in pts who achieved low proteinuria vs those who did not; notably, in pts who achieved CR, the mean rate of kidney function decline (eGFR chronic slope) was <1.0 mL/min/ 1.73 m 2 /y.As SPAR-treated pts achieved proteinuria remission more frequently vs IRB in PROTECT, this analysis further supports the benefit of SPAR for long-term preservation of kidney function.

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Publication Details

Journal
Kidney International Reports
Published
2025-01-27
DOI
https://doi.org/10.1016/j.ekir.2024.11.395
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
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article

WCN25-1933 WHEN THE SPIKES ARE NOT MEMBRANOUS: AN UNUSUAL PRESENTATION OF FIBRILLARY GLOMERULONEPHRITIS

Evamaria Anvari, Paavana Varanasi, Maggie Ryan
Kidney International Reports
Amyloidosis: Diagnosis, Treatment, Outcomes
article

WCN25-1933 WHEN THE SPIKES ARE NOT MEMBRANOUS: AN UNUSUAL PRESENTATION OF FIBRILLARY GLOMERULONEPHRITIS

Evamaria Anvari, Paavana Varanasi, Maggie Ryan
article en

Abstract

eGFR over time were substantially lower in pts with CR or UPE <0.5 g/ d vs those who did not achieve these targets.Conclusions: In IgAN, achievement of low proteinuria is strongly predictive of better long-term kidney function.eGFR preservation was more evident in pts who achieved low proteinuria vs those who did not; notably, in pts who achieved CR, the mean rate of kidney function decline (eGFR chronic slope) was <1.0 mL/min/ 1.73 m 2 /y.As SPAR-treated pts achieved proteinuria remission more frequently vs IRB in PROTECT, this analysis further supports the benefit of SPAR for long-term preservation of kidney function.

Kidney International ReportsVol. 10(2)
Mayo Clinic in Arizona (US)
Openalex Percentile: Top 99%
Amyloidosis: Diagnosis, Treatment, Outcomes
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