WCN25-1933 WHEN THE SPIKES ARE NOT MEMBRANOUS: AN UNUSUAL PRESENTATION OF FIBRILLARY GLOMERULONEPHRITIS
eGFR over time were substantially lower in pts with CR or UPE <0.5 g/ d vs those who did not achieve these targets.Conclusions: In IgAN, achievement of low proteinuria is strongly predictive of better long-term kidney function.eGFR preservation was more evident in pts who achieved low proteinuria vs those who did not; notably, in pts who achieved CR, the mean rate of kidney function decline (eGFR chronic slope) was <1.0 mL/min/ 1.73 m 2 /y.As SPAR-treated pts achieved proteinuria remission more frequently vs IRB in PROTECT, this analysis further supports the benefit of SPAR for long-term preservation of kidney function.
Authors
- Evamaria Anvari (ORCID: https://orcid.org/0000-0002-5260-3511)
- Paavana Varanasi (ORCID: https://orcid.org/0000-0001-9669-397X)
- Maggie Ryan
Institutions
- Mayo Clinic in Arizona (US)
Publication Details
- Journal
- Kidney International Reports
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1016/j.ekir.2024.11.395
- Primary Topic
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00