Myocardial Inflammation in Cardiac Transthyretin Amyloidosis: Prevalence and Potential Prognostic Implications
Our findings affirm previous evidence that myocardial inflammation is present in approximately one-third of all patients with ATTR-CA. Moreover, we provide first data indicating that myocardial inflammation may be associated with a higher risk of death and heart failure hospitalizations in ATTR-CA.
Authors
- Bettina Heidecker (ORCID: https://orcid.org/0000-0002-3811-7920)
- Joshua D. Mitchell (ORCID: https://orcid.org/0000-0001-7371-5742)
- Maximilian Leo Müller (ORCID: https://orcid.org/0000-0002-6281-9754)
- Sebastian Spethmann (ORCID: https://orcid.org/0000-0003-0987-8007)
- Isabel Mattig (ORCID: https://orcid.org/0000-0001-8455-3750)
- Karin Klingel (ORCID: https://orcid.org/0000-0003-0203-2498)
- Katrin Hahn (ORCID: https://orcid.org/0000-0002-6013-0072)
- Michele Violano (ORCID: https://orcid.org/0000-0001-8334-4754)
- Daniel Messroghli (ORCID: https://orcid.org/0000-0003-1331-5004)
- Andrea Frustaci (ORCID: https://orcid.org/0000-0002-5748-0725)
- Ulf Landmesser (ORCID: https://orcid.org/0000-0002-0214-3203)
- Joshua M. Hare (ORCID: https://orcid.org/0000-0002-7751-5032)
- Anna Brand (ORCID: https://orcid.org/0000-0002-0383-0347)
- Thomas F. Lüscher
Institutions
- University of Miami (US)
- Washington University in St. Louis (US)
- Royal Brompton & Harefield NHS Foundation Trust (GB)
- Harefield Hospital (GB)
- Humboldt-Universität zu Berlin (DE)
- Center for Prevention and Treatment of Infections (US)
- Molecular Partners (Switzerland) (CH)
- Deutsches Herzzentrum der Charité (DE)
- German Centre for Cardiovascular Research (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- Hertie Institute for Clinical Brain Research (DE)
- Medizinische Universität Lausitz - Carl Thiem (DE)
- Freie Universität Berlin (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Circulation Heart Failure
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1161/circheartfailure.124.012146
- Citations
- 12
- Primary Topic
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 9.67