WCN25-1081 STUDY OF CLINICAL SIGNIFICANCE OF IgM AND C3 GLOMERULAR DEPOSITIS IN PRIMARY FOCAL SEGMENTAL GLOMERULOSCLEROSIS

dysmorphic hematuria.However, patients who did not present dysmorphia had a higher ischemic heart disease (p0.019),antiplatelet agents (p0.016),protein/creatinine ratio (p0.043) and positive urine culture (p 0.046).In the logistic regression analysis, lower protein/creatinine ratio in urine (1.03-9.09OR: 3.06, p0.044) was the only variable associated with the presence of dysmorphia.A ROC curve was obtained with an area under the curve of 0.72 (0.619-0.822 p<0.001).The sensitivity was 31.9% and specificity of 91.5%.Conclusions: In our cohort diagnosed with GN and microhematuria, dysmorphia was detected in approximately half of patients.The absence of hypertension, ischemic heart disease, antiplatelet agents, negative urine culture and lower level of proteinuria were related to the presence of dysmorphia, with a sensitivity of 31.9% and a specificity of 91.5%.I have no potential conflict of interest to disclose.I did not use generative AI and AI-assisted technologies in the writing process.

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Publication Details

Journal
Kidney International Reports
Published
2025-01-27
DOI
https://doi.org/10.1016/j.ekir.2024.11.371
Primary Topic
IgG4-Related and Inflammatory Diseases
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article
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article

WCN25-1081 STUDY OF CLINICAL SIGNIFICANCE OF IgM AND C3 GLOMERULAR DEPOSITIS IN PRIMARY FOCAL SEGMENTAL GLOMERULOSCLEROSIS

CHINMAY KUMAR, K. Jagan Babu, Prajit Mazumdar, INDERJITG MOMIN
Kidney International Reports
IgG4-Related and Inflammatory Diseases
article

WCN25-1081 STUDY OF CLINICAL SIGNIFICANCE OF IgM AND C3 GLOMERULAR DEPOSITIS IN PRIMARY FOCAL SEGMENTAL GLOMERULOSCLEROSIS

CHINMAY KUMAR, K. Jagan Babu, Prajit Mazumdar, INDERJITG MOMIN
article en

Abstract

dysmorphic hematuria.However, patients who did not present dysmorphia had a higher ischemic heart disease (p0.019),antiplatelet agents (p0.016),protein/creatinine ratio (p0.043) and positive urine culture (p 0.046).In the logistic regression analysis, lower protein/creatinine ratio in urine (1.03-9.09OR: 3.06, p0.044) was the only variable associated with the presence of dysmorphia.A ROC curve was obtained with an area under the curve of 0.72 (0.619-0.822 p<0.001).The sensitivity was 31.9% and specificity of 91.5%.Conclusions: In our cohort diagnosed with GN and microhematuria, dysmorphia was detected in approximately half of patients.The absence of hypertension, ischemic heart disease, antiplatelet agents, negative urine culture and lower level of proteinuria were related to the presence of dysmorphia, with a sensitivity of 31.9% and a specificity of 91.5%.I have no potential conflict of interest to disclose.I did not use generative AI and AI-assisted technologies in the writing process.

Kidney International ReportsVol. 10(2)
BLK Super Speciality Hospital (IN), Yashoda Hospital (IN)
Zero hunger
Openalex Percentile: Top 98%
IgG4-Related and Inflammatory Diseases
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