WCN25-1035 Association between Anti-Erythropoietin Receptor Antibodies and Cardiac Function in Patients on Hemodialysis: A Multi-center Cross-Sectional Study

Cardiac dysfunction is an important prognostic predictor of cardiovascular mortality in patients on hemodialysis (HD). Erythropoietin (EPO) has been reported to improve cardiac function by binding to the EPO receptor (EPOR) on cardiomyocytes. This study investigated whether anti-EPOR antibodies were associated with left ventricular cardiac function (mass index [LVMI] and ejection fraction [LVEF]) in patients undergoing HD.

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Publication Details

Journal
Kidney International Reports
Published
2025-01-27
DOI
https://doi.org/10.1016/j.ekir.2024.11.617
Primary Topic
Erythropoietin and Anemia Treatment
Type
article
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article

WCN25-1035 Association between Anti-Erythropoietin Receptor Antibodies and Cardiac Function in Patients on Hemodialysis: A Multi-center Cross-Sectional Study

Yasunori Iwata, Kunihiro Ishioka, Shuzo Kobayashi, Takayasu Ohtake et al.
Kidney International Reports
Erythropoietin and Anemia Treatment
article

WCN25-1035 Association between Anti-Erythropoietin Receptor Antibodies and Cardiac Function in Patients on Hemodialysis: A Multi-center Cross-Sectional Study

Yasunori Iwata, Kunihiro Ishioka, Shuzo Kobayashi, Takayasu Ohtake, Megumi Oshima, Sumi Hidaka, Norihiko Sakai, Takashi Wada, Miho Shimizu, Yoshitaka Koshino, Machiko Oka, Shinji Kitajima, Yasuhiro Mochida, Hidekazu Moriya, Akinori Hara, Tadashi Toyama
article en

Abstract

Cardiac dysfunction is an important prognostic predictor of cardiovascular mortality in patients on hemodialysis (HD). Erythropoietin (EPO) has been reported to improve cardiac function by binding to the EPO receptor (EPOR) on cardiomyocytes. This study investigated whether anti-EPOR antibodies were associated with left ventricular cardiac function (mass index [LVMI] and ejection fraction [LVEF]) in patients undergoing HD.

Kidney International ReportsVol. 10(2)
Kanazawa University (JP), Shonan Kamakura General Hospital (JP)
Good health and well-being
Openalex Percentile: Top 98%
Erythropoietin and Anemia Treatment
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