WCN25-3229 BREAKING DISEASE BARRIERS: A CASE OF ANTI-PLA2R POSITIVE MEMBRANOUS NEPHROPATHY FOLLOWING ALLOGENEIC STEM CELL TRANSPLANTATION

Membranous nephropathy (MN) is considered a rare manifestation of chronic graft versus host disease (cGvHD) after allogeneic hematopoietic stem cell transplantation (HSCT). MN results from antibody generation to glomerular antigens, such as Phospholipase A2 receptor (PLA2R) or the recently described protocadherin FAT1, an antigen exclusively identified in post-HSCT patients. Although anti-PLA2R antibodies are quite common in non HSCT-MN patients, they have not been described in a patient post-HSCT.