WCN25-4517 A TALE OF TWO BIOPSIES: REVISITING LUPUS NEPHRITIS
The kidney biopsy (KB) remains the gold standard for diagnosing and evaluating lupus nephritis (LN) inflammatory activity and chronic damage. The usefulness of repeat KB is still a matter of debate for assessing response to therapy; differentiating proteinuria from inflammation or chronic damage; and monitoring drug tapering and suspension. The aim of this study was to evaluate LN patients who underwent a second KB, examining the reasons for performing repeat biopsies, the changes in histopathology, and the shifts in activity and chronicity indices, to determine the clinical significance of this procedure.
Authors
- Helena Brandão Viana (ORCID: https://orcid.org/0000-0002-2018-202X)
- Bárbara Beirão (ORCID: https://orcid.org/0000-0002-0910-6018)
- Henrique Borges (ORCID: https://orcid.org/0000-0002-0729-5767)
- Mário Góis
- Joana Medeiros (ORCID: https://orcid.org/0000-0001-6698-1700)
Institutions
- Hospital de São José (PT)
- Algarve Biomedical Center (PT)
- Association for the Development of Douro Viticulture (PT)
- Hospital Braga (PT)
- Clinical Academic Center of Braga (PT)
- University of Algarve (PT)
Publication Details
- Journal
- Kidney International Reports
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1016/j.ekir.2024.11.458
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00