WCN25-1409 CARDIOVASCULAR DISEASE, DIABETES FOLLOWED BY MALIGNANCY ARE THE MOST COMMON COMORBIDITIES AFFECTING EVALUATION FOR KIDNEY TRANSPLANTATION- DATA FROM LARGEST POPULATION OF HEMODIALYSIS SUBJECTS IN POLAND

Results: Six combined liver-kidney transplantations were performed in the same period, which corresponds to 1% and 10 % of the kidney and liver transplants, respectively.5 were male (83.3 %) and one was female (16.6%).4 patients undergone deceased donor transplantation and 2 patients undergone live donor transplantation.The average patients and donors age was 44.83AE2 and 30.7 AE2 , respectively.The MELD score mean was 25 AE4.2 .Primary hyperoxaluria both type 1 and type 2 were indications for two patients .The main cause of liver dysfunction were NASH (n3), HCV related (1) .As for renal dysfunction, diabetic nephropathy (n2) was the most frequent.The mean liver cold and warm ischemic time was 80 mins .and 29.2 AE 7.9 minutes, respectively.The average length of hospital stay was 30 days Surgical complications occurred in one patient; he had hepatic artery thrombosis for which thrombolysis was done .One patient had liver rejection which was treated .In two cases was observed acute renal allograft dysfunction of which one was due to Tacrolimus toxicity and other due to cellular rejection.Intensive preoperative high flux dialysis and intraop CRRT done for 2 patients with primary hyperoxaluria to reduce oxalate load.There was one death (14%) due to sepsis .Surviving 5 patients have stable liver and kidney graft function..The three year survival rate in patients was 80 %.Conclusions: In conclusion ,Simultaneous liver and kidney transplantation (SLKT) is a safe and viable option for liver transplant candidates with end-stage kidney disease (ESKD) and sustained acute kidney injury (AKI) unlikely to recover after liver transplantation, and those with inborn metabolic diseases to help mitigate the risk of posttransplant renal dysfunction.I have no potential conflict of interest to disclose.I did not use generative AI and AI-assisted technologies in the writing process.