WCN25-950 CLINICAL PROFILE AND EFFECTIVENESS OF THERAPY IN PLA2R ASSOCIATED MEMBRANOUS GLOMERULONEPHRITIS: AN AMBISPECTIVE STUDY
Membranous nephropathy, an important cause of adult nephrotic syndrome, is a disorder of IgG immune complex-based thickening of the glomerular capillary wall. This leads to podocyte structural damage and proteinuria. Being autoimmune in origin, podocytes are the source of autoantigens and the target of circulating autoantibodies. Though the definitive diagnosis is made by typical histopathological findings on kidney biopsy, PLA2R antibody positivity is a useful diagnostic marker for its diagnosis.
Authors
- Sukhwinder Singh Sangha (ORCID: https://orcid.org/0000-0003-2805-2323)
- Ram B. Singh (ORCID: https://orcid.org/0000-0002-4922-0405)
- Sudheendra N.R. Rao (ORCID: https://orcid.org/0000-0001-7576-1718)
- Samriti Gupta (ORCID: https://orcid.org/0000-0002-9830-1471)
- Kush Dev Singh Jarial
- Sartaj Hussain (ORCID: https://orcid.org/0000-0003-0582-6808)
- Asheesh Kumar (ORCID: https://orcid.org/0000-0002-0592-0629)
Institutions
- All India Institute of Medical Sciences Jodhpur (IN)
- Indira Gandhi Medical College (IN)
- Sri Devaraj Urs Academy of Higher Education and Research (IN)
- Command Hospital (IN)
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- Kidney International Reports
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1016/j.ekir.2024.11.1014
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 0.00