WCN25-4201 POST-PARTUM THROMBOTIC MICROANGIOPATHY: IN THE ERA OF COMPLEMENT INHIBITORS, PLASMA EXCHANGE IS STILL WORTH TRYING IN DEVELOPING COUNTRIES

Physical Functioning (mean score increased from 32.72 to 52.66, P < 0.001), Role Physical (31.08 to 46.90, P < 0.001), and Energy (28.64 to 51.66, P < 0.001).Emotional recovery was also prominent, with Role Emotional scores improving from 28.18 to 50.32 (P < 0.001), and Emotional Well-being from 31.69 to 48.76 (P < 0.001).Though there was significant improvement in domain functioning by 3 months, the comparison between 3 and 12 months showed a plateau, with no further statistically significant improvement in any domain.Physical Functioning scores slightly decreased from 52.66 to 49.97, and General Health remained stable at 50.12 to 50.06 (P > 0.95 for all domains).Renal replacement therapy was required in 77% of the patients.Overall, there was a notable lack of further improvement in QOL at 12 months, indicating that despite initial gains, the long-term recovery was limited.Conclusions: The study demonstrates that women recovering from PRAKI experience significant improvements in quality of life within the first 3 months postpartum.The improvement was statistically significant in those with positive pregnancy outcome, familysupportand higher education.However, the plateau in recovery from 3 to 12 months highlights the need for sustained interventions beyond the early recovery phase and including a trained counsellor may be a value addition to post-partum care for ensuring optimal long-term maternal health outcomes.Ours is the first study to assess QOL among Pregnancy-Related Acute Kidney Injury (PRAKI) patients.I have no potential conflict of interest to disclose.I did not use generative AI and AI-assisted technologies in the writing process.