WCN25-297 ETHANOL LOCK VERSUS ANTIBIOTIC LOCK - A PROSPECTIVE RCT TO SALVAGE CATHETERS IN CRBSI IN PATIENTS UNDERGOING MAINTAINENCE HEMODIALYSIS VIA TUNNELED CUFFED CATHETER

Catheter-Related Blood Stream Infection (CRBSI) is one of the major causes of morbidity and mortality in patients undergoing hemodialysis (HD) through Tunneled cuffed catheter (TCC). Majority of CRBSIs are associated with the formation of a microbial biofilm on the device. As systemic antibiotics have limited ability in countering the biofilm, an antibiotic or antiseptic lock has the ability to target the biofilm directly. Different locking solutions have been tried in the past with varying success.