WCN25-3166 IDENTIFYING NOVEL RENAL BIOMARKERS TO IMPROVE THE CLINICAL PHENOTYPING OF PREECLAMPSIA
Preeclampsia (PE) is associated with acute kidney injury, carrying an increased risk of future renal disease. Whilst serum creatinine informs the diagnosis of PE, renal biomarkers are not routinely used for prediction and prognosis of PE. Magnetic resonance imaging (MRI) biomarkers can non-invasively quantify tissue characteristics such as inflammation, oedema and fibrosis. We evaluated maternal renal MRI biomarkers in women at high risk of developing PE to see if they could provide mechanistic insight and improved risk stratification in PE.
Authors
- Josephine H. Naish (ORCID: https://orcid.org/0000-0002-8980-8924)
- Kate Bramham (ORCID: https://orcid.org/0000-0002-6272-7921)
- A. D. Crawford
- Luke Pleva
- Kate Duhig (ORCID: https://orcid.org/0000-0001-9176-5671)
- Jenny Myers (ORCID: https://orcid.org/0000-0003-0913-2096)
- Alexander E. P. Heazell (ORCID: https://orcid.org/0000-0002-4303-7845)
- Kate Wiles (ORCID: https://orcid.org/0000-0003-0617-8144)
- Helena Alderson
Institutions
- King's College London (GB)
- Barts Health NHS Trust (GB)
- Society for Maternal-Fetal Medicine (US)
- University of Manchester (GB)
Publication Details
- Journal
- Kidney International Reports
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1016/j.ekir.2024.11.842
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00