WCN25-4217 CORRELATION OF FRAILTY STATUS AND CLINICAL PARAMETHERS IN A PERITONEAL DIALYSIS PATIENTS COHORT

average alert number, but there was no relationship of alert frequency with risk of technique failure beyond 12 months.This relationship was seen in univariate analyses, and remained so after adjustment for potential confounders.The trend was seen across all-cause and death-censored technique failure, and also among noninfective and infective causes of technique failure (Figure).Conclusions: The number of early alerts reported predicts risk of technique failure among people receiving APD to 12 months, but not beyond.Although this study does not define the mechanism of this relationship, it does lendsupportinterventions targeting interventions to reduce the alert burden in the early stages of therapy.Further analyses will explore relationships of individual alert types and timing with outcomes.I have potential conflict of interest to disclose.This work wassupportby an investigator initiatedgrantfrom BaxterHealthcare.I did not use generative AI and AI-assisted technologies in the writing process.