WCN25-3372 Clinical spectrum of cystic kidney diseases in children and genetic evaluation
On analysis of fetal outcome, live birth occurred in more than half of the mothers( 55%) , while IUD occurred in 225(45%) and preterm babies in 63 mothers(12.6%),respectively.A total of 257(51%) patients had complete renal recover,120(24%) patients died,However 112 patients had persistent renal dysfunction on discharge and 11 were dialysis dependent.Our Praki study group had a mortality of 24%( 120 patients).Elderage,parity status, multiorgan failure with usage of increased organsupports, etiologies of preeclampsia and antepartum haemorrhage and sepsis, were significantly associated with poor survival of Praki.Conclusions: 1.The prevalence of PrAKI was 0.76% among all Pregnancies 2. The incidence of PrAKI was 1% 3. Etiology of PrAKI is multifactorial, Most common cause being Sepsis and associated complications 43%, followed by Sepsis and associated complications27%.4. In 21% of patients Sepsis was coexisting with Preeclampsia 5.Factors associated with poor maternal outcomes are Elderage,parity status, multiorgan failure with usage of increased organsupports, etiologies of preeclampsia and antepartum haemorrhage and sepsis.6. Factors associated with poor fetal oucomes are preeclampsia, multiparity, Abrution.Limitations:1. longterm Follow up couldn't be done for the patients 2. Biopsy was done in very few patients.I have no potential conflict of interest to disclose.I did not use generative AI and AI-assisted technologies in the writing process.
Authors
- Monika Gulia (ORCID: https://orcid.org/0000-0002-7114-4904)
- Sidharth Kumar Sethi (ORCID: https://orcid.org/0000-0002-1516-3393)
- Shyam Bihari Bansal
Institutions
- Medanta The Medicity (IN)
Publication Details
- Journal
- Kidney International Reports
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1016/j.ekir.2024.11.1079
- Primary Topic
- Genetic and Kidney Cyst Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00