WCN25-3712 CRYOGLOBULINEMIC GLOMERULONEPHRITIS AND VASCULITIS IN THE SETTING OF SJOGREN'S SYNDROME

Sjogren’s syndrome (SjS) is a systemic autoimmune disease characterized by infiltration of lymphocytes in exocrine glands, primarily the lacrimal and salivary ones. A subset of patients with SjS will also have extraglandular manifestations. The most common kidney disease in SjS is tubulointerstitial nephritis, with patients often presenting with electrolyte derangements secondary to renal tubular acidosis or nephrogenic diabetes insipidus. Less commonly, glomerular involvement in patients with SjS will present with acute kidney injury (AKI) and nephrotic syndrome.