Optical coherence tomography guided automatic robotic craniotomy surgery platform
A transparent craniotomy window is required for optical brain imaging; however, traditional surgical preparation requires well-trained surgeons, is time-consuming, and suffers from low success rates. To address this issue, we present an automatic craniotomy platform combining optical coherence tomography (OCT) with an automated drilling machine. The OCT provides 3D skull data to guide a homemade closed-loop high-precision drill for controlled craniotomies, achieving a 100% success rate in creating small, large, and thinned windows. A synthetic transparent window was installed after skull excision. This system enables high-quality OCT angiography, velocimetry, and ultrasound imaging, offering an efficient tool for brain research.
Authors
- Yanxiang Bao
- Huijuan Feng (ORCID: https://orcid.org/0000-0002-1606-731X)
- Jianbo Tang (ORCID: https://orcid.org/0000-0001-6532-8283)
- Junxiong Zhou
- Shiteng Suo (ORCID: https://orcid.org/0000-0003-2528-2836)
- Wei Chen (ORCID: https://orcid.org/0000-0003-1624-8492)
- Heng Sun
- Wenjin Wang (ORCID: https://orcid.org/0000-0001-7832-5444)
- Haoyuan Li (ORCID: https://orcid.org/0000-0001-7527-9737)
- Lu Xu (ORCID: https://orcid.org/0000-0003-3944-2175)
- Yanjun Zhang (ORCID: https://orcid.org/0000-0003-3095-625X)
- Y. J. Bi
- Yongchao Wang (ORCID: https://orcid.org/0000-0002-6637-0157)
- Xiangsen Guo (ORCID: https://orcid.org/0009-0006-3357-810X)
Institutions
- Harbin Medical University (CN)
- AgroParisTech (FR)
- Southern University of Science and Technology (CN)
- Roosevelt Hospital (GT)
- Fourth Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Biomedical Optics Express
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1364/boe.549260
- Citations
- 2
- Primary Topic
- Retinal Imaging and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 2.72
Funders
- National Natural Science Foundation of China
- Ministry of Science and Technology of the People's Republic of China
- Science, Technology and Innovation Commission of Shenzhen Municipality