Low-level tragus stimulation as a treatment for primary hypertension: a systemic reaction with a broader cardioprotective potential?

Low-level tragus stimulation (LL-TS) as a noninvasive technique of vagus nerve stimulation (VNS) moves to the fore in the autonomic nervous system (ANS) studies as a nondrug based, easy applicable tool. LL-TS triggering a complex systemic response may offer a broader cardioprotective potential than expected as a recent investigation outlined blood pressure (BP) reduction by LL-TS in patients with hypertension, which is commonly related to imbalance of the ANS as several other cardiovascular diseases.