Obstructive sleep apnea and structural and functional brain alterations: a brain-wide investigation from clinical association to genetic causality
Nerve fiber damage and imbalances in neuronal activity across multiple brain regions caused by hypoxia, particularly the frontal lobe, underlie the structural and the functional connectivity impairments in OSA.
Authors
- Yuhong Pi
- Nuofu Zhang (ORCID: https://orcid.org/0000-0003-1998-9958)
- Qiming Gan
- Xiaofen Su (ORCID: https://orcid.org/0000-0001-6354-5794)
- Xinni Wang (ORCID: https://orcid.org/0009-0006-1376-6082)
- Sun Zhang (ORCID: https://orcid.org/0009-0009-7330-7728)
- Wenjin Zou (ORCID: https://orcid.org/0000-0002-1768-5793)
- Kang Wu (ORCID: https://orcid.org/0009-0000-3249-842X)
- Yanjuan Wu (ORCID: https://orcid.org/0000-0002-5208-1231)
- Xinchun Li (ORCID: https://orcid.org/0009-0005-5613-2613)
Institutions
- First Affiliated Hospital of Guangzhou Medical University (CN)
- State Key Laboratory of Respiratory Disease (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1186/s12916-025-03876-8
- Citations
- 16
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 18.63
Funders
- National Natural Science Foundation of China