miR-208a-3p discriminates osteoporosis, predicts fracture, and regulates osteoclast activation through targeting STC1
Serum miR-208a-3p served as a diagnostic biomarker for OP and a risk factor for fracture in post-menopausal women. miR-208a-3p regulated macrophage inflammation and further mediated osteoclast activation via targeting STC1.
Authors
- Haohua Qian (ORCID: https://orcid.org/0000-0002-1114-4697)
- Fei Jia (ORCID: https://orcid.org/0000-0002-7121-479X)
- Huiling Qin (ORCID: https://orcid.org/0009-0005-5287-0192)
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Shandong Provincial Hospital (CN)
- Traditional Chinese Medicine Hospital of Kunshan (CN)
- Affiliated Hospital of Youjiang Medical University for Nationalities (CN)
- Baise University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1186/s13018-025-05512-w
- Citations
- 2
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Natural Science Foundation of Shandong Province