Towards evaluating and building versatile large language models for medicine

In this study, we present MedS-Bench, a comprehensive benchmark to evaluate large language models (LLMs) in clinical contexts, MedS-Bench, spanning 11 high-level clinical tasks. We evaluate nine leading LLMs, e.g., MEDITRON, Llama 3, Mistral, GPT-4, Claude-3.5, etc. and found that most models struggle with these complex tasks. To address these limitations, we developed MedS-Ins, a large-scale instruction-tuning dataset for medicine. MedS-Ins comprises 58 medically oriented language corpora, totaling 5M instances with 19K instructions, across 122 tasks. To demonstrate the dataset's utility, we conducted a proof-of-concept experiment by performing instruction tuning on a lightweight, open-source medical language model. The resulting model, MMedIns-Llama 3, significantly outperformed existing models on various clinical tasks. To promote further advancements, we have made MedS-Ins fully accessible and invite the research community to contribute to its expansion. Additionally, we have launched a dynamic leaderboard for MedS-Bench, to track the development progress of medical LLMs.

Authors

Institutions

Publication Details

Journal
npj Digital Medicine
Published
2025-01-27
DOI
https://doi.org/10.1038/s41746-024-01390-4
Citations
26
Primary Topic
Topic Modeling
Type
article
Field-Weighted Citation Impact
64.51

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Towards evaluating and building versatile large language models for medicine

Jinxin Liu, Hongfei Gu, Weidi Xie, Chaoyi Wu et al.
26 citations
npj Digital Medicine
Topic Modeling
64.51
article

Towards evaluating and building versatile large language models for medicine

Jinxin Liu, Hongfei Gu, Weidi Xie, Chaoyi Wu, Ya Zhang, Na Li, Yanfeng Wang, Pengcheng Qiu
article en
26 citations

Abstract

In this study, we present MedS-Bench, a comprehensive benchmark to evaluate large language models (LLMs) in clinical contexts, MedS-Bench, spanning 11 high-level clinical tasks. We evaluate nine leading LLMs, e.g., MEDITRON, Llama 3, Mistral, GPT-4, Claude-3.5, etc. and found that most models struggle with these complex tasks. To address these limitations, we developed MedS-Ins, a large-scale instruction-tuning dataset for medicine. MedS-Ins comprises 58 medically oriented language corpora, totaling 5M instances with 19K instructions, across 122 tasks. To demonstrate the dataset's utility, we conducted a proof-of-concept experiment by performing instruction tuning on a lightweight, open-source medical language model. The resulting model, MMedIns-Llama 3, significantly outperformed existing models on various clinical tasks. To promote further advancements, we have made MedS-Ins fully accessible and invite the research community to contribute to its expansion. Additionally, we have launched a dynamic leaderboard for MedS-Bench, to track the development progress of medical LLMs.

npj Digital MedicineVol. 8(1)
China Mobile (China) (CN), Shanghai Jiao Tong University (CN), Beijing Academy of Artificial Intelligence (CN), Shanghai Artificial Intelligence Laboratory (CN)
Science and Technology Commission of Shanghai Municipality, National Key Research and Development Program of China
Quality Education
Openalex Percentile: Top 0%
Topic Modeling
64.51
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Towards evaluating and building versatile large language models for medicine — Jinxin Liu, Hongfei Gu, et al. · npj Digital Medicine (2025) | TGRS Research Map | TGRS