Prophylactic and therapeutic effects of EsV3 on atherosclerotic lesions in ApoE−/− mice
In ApoE<sup>-/-</sup> hyperlipidemic mice, EsV3 improved lipid profiles and reduced aortic plaque formation. EsV3's effects, attributed partly to its antioxidant properties, were comparable to atorvastatin, suggesting its potential as a preventive and therapeutic agent for hyperlipidemia and atherosclerosis.
Authors
- Rebecca Wu (ORCID: https://orcid.org/0000-0002-8065-4498)
- Rong Xu (ORCID: https://orcid.org/0000-0001-7947-2788)
- Yuanyuan Wang (ORCID: https://orcid.org/0000-0002-0641-8411)
- Hui Liu (ORCID: https://orcid.org/0000-0002-7669-9386)
- Hifumi Ohishi
Institutions
- Huazhong Agricultural University (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- BMC Cardiovascular Disorders
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1186/s12872-025-04497-y
- Citations
- 1
- Primary Topic
- Atherosclerosis and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.80