Synthesis of 2-(4-Methyl-Phenoxymethyl) Benzoic Acid; Cresol and its Metal Coordinate Complexes

A series of phenoxymethylbenzoic acid derivatives were synthesized by reacting p-cresol with phthalide. The resulting phenoxymethyl benzoic acid was converted into corresponding acid chloride by reacting with cyanuric chloride. These phenoxymethyl benzoyl chlorides were then reacted with various aminobenzenesulfonamides and synthesize d new sulfonamide derivatives. The targeted sulfonamides were subjected to structural characterization by contemporary spectroscopic techniques like UV-visible and FT-IR. The presence of a peak at 3400/cm confirmed the existence of amide functionality, and furthermore , the broad peak at1250/cm showed that the sulfone group is present in the molecule.

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Journal
FRONTIERS IN CHEMICAL SCIENCES
Published
2024-12-30
DOI
https://doi.org/10.52700/fcs.v5i2.98
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1
Primary Topic
Analytical Chemistry and Chromatography
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article
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0.24
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article

Synthesis of 2-(4-Methyl-Phenoxymethyl) Benzoic Acid; Cresol and its Metal Coordinate Complexes

Ghulam Shabir, Aamer Saeed, Muhammad Sajid Nadeem, Fakiha Nazakat et al.
1 citations
FRONTIERS IN CHEMICAL SCIENCES
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article

Synthesis of 2-(4-Methyl-Phenoxymethyl) Benzoic Acid; Cresol and its Metal Coordinate Complexes

Ghulam Shabir, Aamer Saeed, Muhammad Sajid Nadeem, Fakiha Nazakat, Nasir Abbas, S.A. Waheed, Sidra Ghafoor
article en
1 citations

Abstract

A series of phenoxymethylbenzoic acid derivatives were synthesized by reacting p-cresol with phthalide. The resulting phenoxymethyl benzoic acid was converted into corresponding acid chloride by reacting with cyanuric chloride. These phenoxymethyl benzoyl chlorides were then reacted with various aminobenzenesulfonamides and synthesize d new sulfonamide derivatives. The targeted sulfonamides were subjected to structural characterization by contemporary spectroscopic techniques like UV-visible and FT-IR. The presence of a peak at 3400/cm confirmed the existence of amide functionality, and furthermore , the broad peak at1250/cm showed that the sulfone group is present in the molecule.

FRONTIERS IN CHEMICAL SCIENCESVol. 5(2)
Quaid-i-Azam University (PK), Government College University, Faisalabad (PK), Forman Christian College (PK)
Openalex Percentile: Top 46%
Analytical Chemistry and Chromatography
0.24
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