Cover Feature: Total Synthesis of (15<i>R</i>)‐ and (15<i>S</i>)‐Prostaglandin A<sub>2</sub> (Chem. Eur. J. 50/2024)
An aquarium contains the materials for synthesizing the marine natural products (15S)- and (15R)-prostaglandin A2. Both epimers can be isolated from the sea whip Plexaura homomalla. While the (15S)-prostaglandin A2 (left) significantly reduced GABA-induced currents through GABAA receptors, its 15R epimer (right) did not show any significant effect. The bubbler on the left side is shaped like Spittelau, a Viennese landmark located near the lab. More information can be found in the Research Article by N. Schützenmeister and co-workers (DOI: 10.1002/chem.202401921).
Authors
- Ernst Urban (ORCID: https://orcid.org/0009-0000-1339-836X)
- Sophia Khom (ORCID: https://orcid.org/0000-0003-3567-8973)
- Christoph Alberti (ORCID: https://orcid.org/0000-0002-2153-4824)
- Nina Schützenmeister (ORCID: https://orcid.org/0000-0001-9608-0057)
- Katharina Neßmerak
- Theresa Bock
- Justus Lackner
Institutions
- University of Vienna (AT)
- Universität Hamburg (DE)
Publication Details
- Journal
- Chemistry - A European Journal
- Published
- 2024-09-05
- DOI
- https://doi.org/10.1002/chem.202485003
- Primary Topic
- Inflammatory mediators and NSAID effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00