SPECIES COMPOSITION AND ANTIBIOTIC RESISTANCE OF BACTERIAL ISOLATES ISOLATED FROM ANIMALS OF THE OMSK REGION

The purpose of research is to study the species composition of microorganisms isolated from agricultural and small domestic animals of the Omsk Region in 2022, to determine the sensitivity to antibacterial agents of prevailing crops in the general structure of isolates. The bacteriological study was carried out on the basis of the Omsk Regional Veterinary Laboratory according to the current methods for the isolation, identification and determination of the sensitivity of microorganisms to antibacterial drugs. The material of the study was samples of clinical material (106) taken from agricultural and small domestic animals in various geographical regions of the Omsk Region. Cultures of etiologically significant microorganisms belonging to the genera were isolated: Staphylococcus, Escherichia, Proteus, Enterococcus, Streptococcus, Enterobacter, Bordetella, Citrobacter, Salmonella, Morganella, Neisseria, Malassezia, Listeria, Bacillus, Klebsiella. In the general structure of the obtained cultures microorganisms of the genus Staphylococcus (36 %) and Escherichia dominated (22 %). Based on the data obtained, a study was made of the antibiotic resistance of the isolated microorganisms of the genus Staphylococcus and the species Escherichia coli to antibacterial agents by the disk-diffusion method on the Givental-Vedmina medium. As a result of the study, it was found that the highest resistance of these microorganisms was recorded to cephalexin, streptomycin, pefloxacin, kanamycin. Further study of the phenomenon of antibiotic resistance of microorganisms opens up great opportunities for improving the effectiveness of therapy for bacterial animal diseases. Specialists in clinical veterinary practice need to take into account the sensitivity to antibiotics in each case of animal disease with bacterial diseases. Such a conscious approach to prescribing antibiotic therapy in the future will lead to a decrease in the accumulation of antibiotic resistance genes among circulating strains of microorganisms.