High-Dose Insulin Therapy for Refractory Shock in a Polypharmacy Overdose of Calcium Channel Blocker and Oral Hypoglycemic Agent: A Case Report and Literature Review

We report a case of polypharmacy overdose involving a calcium (Ca) channel blocker and an oral hypoglycemic agent, where conventional therapies failed to obtain the desired clinical outcome. High-dose insulin (HDI) therapy, a promising treatment regime in this regard, was carried out for our patient, and her condition improved over the subsequent days.