Influence of Retrodipeptide Analogue of Cholecystokinin Tetrapeptide (GB-115) and Phenazepam on the Behavior of Rhesus Monkeys under Isolation Conditions

A positive effect of GB-115 upon subchronic administration on the attenuation of the emotional stress response and the restoration of adaptive behavior in rhesus monkeys comparable to the effect of phenazepam was revealed, which confirms the possibility of using blockade of CCK1 receptors as one of the approaches for treating anxiety disorders.

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Publication Details

Journal
Doklady Biochemistry and Biophysics
Published
2025-01-22
DOI
https://doi.org/10.1134/s1607672924701254
Citations
1
Primary Topic
Neuropeptides and Animal Physiology
Type
article
Field-Weighted Citation Impact
0.91
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article

Influence of Retrodipeptide Analogue of Cholecystokinin Tetrapeptide (GB-115) and Phenazepam on the Behavior of Rhesus Monkeys under Isolation Conditions

С. Б. Середенин, Л. Г. Колик, Е В Черкашина, М.Ф. Тимина et al.
1 citations
Doklady Biochemistry and Biophysics
Neuropeptides and Animal Physiology
0.91
article

Influence of Retrodipeptide Analogue of Cholecystokinin Tetrapeptide (GB-115) and Phenazepam on the Behavior of Rhesus Monkeys under Isolation Conditions

С. Б. Середенин, Л. Г. Колик, Е В Черкашина, М.Ф. Тимина, Alla V. Panchenko, Laura E. Pavlova, An. V. Panchenko
article en
1 citations

Abstract

A positive effect of GB-115 upon subchronic administration on the attenuation of the emotional stress response and the restoration of adaptive behavior in rhesus monkeys comparable to the effect of phenazepam was revealed, which confirms the possibility of using blockade of CCK1 receptors as one of the approaches for treating anxiety disorders.

Doklady Biochemistry and BiophysicsVol. 520(1)
Medical Technologies (Czechia) (CZ)
Zero hunger
Openalex Percentile: Top 31%
Neuropeptides and Animal Physiology
0.91
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