Minimal residual ascites 3 months after TIPS implantation implicates worse clinical outcomes in patients with cirrhosis
This study evaluated the prognostic relevance of residual ascites grades in patients with advanced chronic liver disease after TIPS placement. Severe ascites was linked to the worst outcomes, underscoring the need for urgent liver transplantation evaluation. However, even minimal residual ascites significantly increased the risk of further decompensation and transplant-free mortality. These findings suggest that patients with minimal residual ascites will benefit from enhanced post-TIPS clinical monitoring. Further research is warranted to uncover the underlying mechanisms and investigate the potential of targeted interventions to improve outcomes in this vulnerable group.
Authors
- Mattias Mandorfer (ORCID: https://orcid.org/0000-0003-2330-0017)
- Michael Schwarz (ORCID: https://orcid.org/0000-0002-2587-1385)
- Lukas Reider
- Nina Dominik (ORCID: https://orcid.org/0009-0009-4615-915X)
- Bernhard Meyer (ORCID: https://orcid.org/0000-0001-6486-7955)
- Lukas Hartl (ORCID: https://orcid.org/0000-0003-3398-6120)
- Benjamin Maasoumy (ORCID: https://orcid.org/0000-0002-3250-3177)
- Tammo Lambert Tergast (ORCID: https://orcid.org/0000-0003-3908-6297)
- Andrea Kornfehl
- Heiner H. Wedemeyer (ORCID: https://orcid.org/0000-0003-2906-0480)
- Thomas Reiberger (ORCID: https://orcid.org/0000-0002-4590-3583)
- Theresa Bucsics (ORCID: https://orcid.org/0000-0003-3901-4111)
- Mathias Jachs (ORCID: https://orcid.org/0000-0003-2871-4147)
- Michael A Trauner (ORCID: https://orcid.org/0000-0002-1275-6425)
- Jim Benjamin Mauz
- Paul Hemetsberger
- Anja Tiede
- Georg Kramer (ORCID: https://orcid.org/0009-0008-1736-3699)
- Hannah Rieland
- Sarah Lisa Schütte
Institutions
- Medizinische Hochschule Hannover (DE)
- German Center for Infection Research (DE)
- Medical University of Vienna (AT)
Publication Details
- Journal
- JHEP Reports
- Published
- 2025-01-23
- DOI
- https://doi.org/10.1016/j.jhepr.2025.101335
- Citations
- 3
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 3.97
Funders
- Medizinischen Hochschule Hannover