18F-FDG PET/CT Versus 18F-FAPI PET/CT in Eosinophilic Liver Infiltration

A 48-year-old man presented with upper abdominal discomfort for 10 days. Abdominal contrast-enhanced CT showed multiple abnormal enhanced masses in liver, suggesting a probability of malignancies. The patient was then enrolled in a clinical trial of comparison of 18 F-FDG and 18 F-FAPI PET/CT in hepatic lesions. Compared with 18 F-FDG PET/CT, 18 F-FAPI PET/CT showed higher tracer uptake, more lesions in liver. Meanwhile, peripheral blood eosinophils increased remarkably. The hepatic lesions were highly suspected as eosinophilic liver infiltration. Finally, pathologic analysis confirmed the diagnosis of eosinophilic liver infiltration.

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Journal
Clinical Nuclear Medicine
Published
2025-01-23
DOI
https://doi.org/10.1097/rlu.0000000000005675
Citations
4
Primary Topic
Peptidase Inhibition and Analysis
Type
article
Field-Weighted Citation Impact
4.18
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article

18F-FDG PET/CT Versus 18F-FAPI PET/CT in Eosinophilic Liver Infiltration

Jiucen Liang, Rusen Zhang, Haipeng Chen, Shuyi Li et al.
4 citations
Clinical Nuclear Medicine
Peptidase Inhibition and Analysis
4.18
article

18F-FDG PET/CT Versus 18F-FAPI PET/CT in Eosinophilic Liver Infiltration

Jiucen Liang, Rusen Zhang, Haipeng Chen, Shuyi Li, Hui Zeng
article en
4 citations

Abstract

A 48-year-old man presented with upper abdominal discomfort for 10 days. Abdominal contrast-enhanced CT showed multiple abnormal enhanced masses in liver, suggesting a probability of malignancies. The patient was then enrolled in a clinical trial of comparison of 18 F-FDG and 18 F-FAPI PET/CT in hepatic lesions. Compared with 18 F-FDG PET/CT, 18 F-FAPI PET/CT showed higher tracer uptake, more lesions in liver. Meanwhile, peripheral blood eosinophils increased remarkably. The hepatic lesions were highly suspected as eosinophilic liver infiltration. Finally, pathologic analysis confirmed the diagnosis of eosinophilic liver infiltration.

Clinical Nuclear MedicineVol. 50(8)
First Affiliated Hospital of Guangdong Pharmaceutical University (CN), Guangzhou Medical University Cancer Hospital (CN), Guangzhou Medical University (CN)
Good health and well-being
Openalex Percentile: Top 7%
Peptidase Inhibition and Analysis
4.18
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