Complete Heart Block: A Rare Initial Presentation of Epstein-Barr Virus-Induced Myocarditis

Myocarditis, a rare but serious condition often caused by viral infections, rarely manifests with cardiac involvement in healthy individuals infected with Epstein-Barr virus (EBV). We present a case of a 51-year-old diabetic presenting with exertional dyspnoea, pleuritic chest pain, and intermittent fever. Investigations revealed elevated C-reactive protein (CRP), brain natriuretic peptide (BNP), high sensitive troponin, creatine kinase (CK) levels, and complete heart block on ECG. Echocardiography showed reduced ejection fraction and cardiac MRI confirmed myocarditis. Epstein-Barr virus was confirmed as the underlying cause. He was treated with prednisone, acyclovir, and a permanent pacemaker. Due to serious complications associated with myocarditis such as acute heart failure and arrhythmias, it is imperative to emphasize the importance of early recognition and timely intervention of atypical presentations.

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Publication Details

Journal
Cureus
Published
2025-01-23
DOI
https://doi.org/10.7759/cureus.77884
Primary Topic
Viral Infections and Immunology Research
Type
article
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article

Complete Heart Block: A Rare Initial Presentation of Epstein-Barr Virus-Induced Myocarditis

Kinza Moin, Tarab Iqbal, Thiagarajan Jaiganesh, R Sudha et al.
Cureus
Viral Infections and Immunology Research
article

Complete Heart Block: A Rare Initial Presentation of Epstein-Barr Virus-Induced Myocarditis

Kinza Moin, Tarab Iqbal, Thiagarajan Jaiganesh, R Sudha, Rabi’u Aliyu Umar
article en

Abstract

Myocarditis, a rare but serious condition often caused by viral infections, rarely manifests with cardiac involvement in healthy individuals infected with Epstein-Barr virus (EBV). We present a case of a 51-year-old diabetic presenting with exertional dyspnoea, pleuritic chest pain, and intermittent fever. Investigations revealed elevated C-reactive protein (CRP), brain natriuretic peptide (BNP), high sensitive troponin, creatine kinase (CK) levels, and complete heart block on ECG. Echocardiography showed reduced ejection fraction and cardiac MRI confirmed myocarditis. Epstein-Barr virus was confirmed as the underlying cause. He was treated with prednisone, acyclovir, and a permanent pacemaker. Due to serious complications associated with myocarditis such as acute heart failure and arrhythmias, it is imperative to emphasize the importance of early recognition and timely intervention of atypical presentations.

CureusVol. 17(1)
University of Sharjah (AE), Tawam Hospital (AE)
Good health and well-being
Openalex Percentile: Top 98%
Viral Infections and Immunology Research
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Complete Heart Block: A Rare Initial Presentation of Epstein-Barr Virus-Induced Myocarditis — Kinza Moin, Tarab Iqbal, et al. · Cureus (2025) | TGRS Research Map | TGRS