A multi-institutional retrospective cohort of adult-onset medulloblastoma in the modern era
There was no benefit of concurrent chemotherapy. Adjuvant chemotherapy was associated with improved overall survival and this effect was driven by select subgroups, specifically those with M0 disease and those with residual tumor. We could not confirm that these associations are independent of the treating institution.
Authors
- Tresa McGranahan (ORCID: https://orcid.org/0000-0003-0472-4252)
- Jason Barber (ORCID: https://orcid.org/0000-0002-3016-7800)
- L. Nicolas Gonzalez Castro (ORCID: https://orcid.org/0000-0001-7699-5188)
- Matthias A. Karajannis (ORCID: https://orcid.org/0000-0002-7151-6528)
- John Yohan Rhee (ORCID: https://orcid.org/0000-0002-2081-5667)
- Seema Nagpal (ORCID: https://orcid.org/0000-0002-0289-2319)
- Michael S. Rutenberg (ORCID: https://orcid.org/0000-0001-6945-7883)
- Kate E. Therkelsen
- Patrick J. Cimino (ORCID: https://orcid.org/0000-0003-0441-4502)
- Helen Alice Shih (ORCID: https://orcid.org/0000-0003-1550-9726)
- Derek S. Tsang (ORCID: https://orcid.org/0000-0002-9762-6901)
- Lynne P. Taylor (ORCID: https://orcid.org/0000-0001-5946-3796)
- Marissa Sherwood (ORCID: https://orcid.org/0000-0001-8522-0982)
- Robert J. Amdur (ORCID: https://orcid.org/0000-0002-9850-0964)
- John J. Herbst
- Alipi V Bonm
- Anurag Sanaf
Institutions
- Brigham and Women's Hospital (US)
- National Institutes of Health (US)
- Allegheny Health Network (US)
- University Health Network (CA)
- Memorial Sloan Kettering Cancer Center (US)
- Harvard University (US)
- University of Washington (US)
- University of Florida Health (US)
- Jacksonville College (US)
- Princess Margaret Cancer Centre (CA)
- University of Florida (US)
- Massachusetts General Hospital (US)
- Swedish Medical Center (US)
- Scripps Clinic Medical Group (US)
- National Institute of Nursing Research (US)
- Dana-Farber Cancer Institute (US)
- Stanford Medicine (US)
- Freedom to Live (US)
- Scripps (United States) (US)
- Office of Extramural Research (US)
- Mayo Clinic in Florida (US)
- Ivy Foundation (US)
- Neurological Surgery (US)
- Stanford University (US)
Publication Details
- Journal
- Neuro-Oncology Advances
- Published
- 2024-12-27
- DOI
- https://doi.org/10.1093/noajnl/vdae231
- Citations
- 2
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.88
Funders
- Brigham and Women's Hospital
- Massachusetts General Hospital
- Memorial Sloan-Kettering Cancer Center
- University of Washington
- Allegheny Health Network
- National Institutes of Health
- National Cancer Institute
- NHLBI Division of Intramural Research