Relationship between transmembrane emp24 domain containing 2 expression and tumor stem cell characteristics in oral cancer
Our data imply that TMED2 stimulates GALNT7 transcription, which in turn amplifies the stem-like characteristics and carcinogenic potential of OC cells. Moreover, the block of TMED2 prevents cancers from growing and spreading <i>in vivo</i>. This finding provides a new therapeutic target for the treatment of OC and highlights the critical role of TMED2 in the condition.
Authors
- Yanhui Wu (ORCID: https://orcid.org/0000-0001-5832-6175)
- Shi Lin Zhang
- Guimei Zou
Institutions
- Nanjing University of Chinese Medicine (CN)
- Jiangsu Cancer Hospital (CN)
Publication Details
- Journal
- CytoJournal
- Published
- 2025-01-22
- DOI
- https://doi.org/10.25259/cytojournal_132_2024
- Citations
- 2
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.61