A rare case of histoplasma and cryptococcus coinfection in an apparently immunocompetent child

ABSTRACT Histoplasma capsulatum and Cryptococcus neoformans fungal infections are mainly found in immunocompromised individuals, especially in patients with HIV/AIDS. However, histoplasma-cryptococcus coinfection in immunocompetent hosts is very rare. This rarity increases the chances of underdiagnosis and poor outcomes. From extensive literature search, 15 cases have been found till now. Among them only one immunocompetent case was reported from Brazil. In Asia, only one case was reported in an AIDS patient from India. Here we report a case first time from India where a six-year-old apparently immunocompetent girl presented with histoplasma-cryptococcus coinfection.