Network pharmacology and molecular analysis of mechanisms underlying the therapeutic effects of Rhubarb in treating atherosclerosis and abdominal aortic aneurysm
This study successfully predicted the molecular functions, pharmacological targets, and pathways associated with Rhubarb for treating AS/AAA. In addition, identified potential active ingredients can be used as a source for AS/AAA drug screening.
Authors
- Xia Wang (ORCID: https://orcid.org/0000-0003-2085-0152)
- Youjie Zeng (ORCID: https://orcid.org/0000-0003-3842-1815)
- Jun Huang (ORCID: https://orcid.org/0000-0001-9207-8953)
- Ren Guo (ORCID: https://orcid.org/0000-0002-3930-6846)
- Huilin Xu (ORCID: https://orcid.org/0000-0003-2557-9752)
- Siyi Zhang (ORCID: https://orcid.org/0000-0002-7730-9546)
- Huilin Lian
Institutions
- Central South University (CN)
- Third Xiangya Hospital (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2025-01-23
- DOI
- https://doi.org/10.1016/j.heliyon.2025.e41906
- Citations
- 4
- Primary Topic
- Apelin-related biomedical research
- Type
- article
- Field-Weighted Citation Impact
- 5.58
Funders
- Natural Science Foundation of Hunan Province