Identification of glycogen synthase kinase 3alpha/beta as a host factor required for HBV transcription using high-throughput screening
Our recombinant HBV-based screening system enables the discovery of new targets. Using our approach, we identified GSK3 inhibitors as potential anti-HBV agents.
Authors
- Ikuo Shoji (ORCID: https://orcid.org/0000-0002-0730-4379)
- Y Naito
- Yusuke Murakami (ORCID: https://orcid.org/0000-0002-3761-1732)
- Hironori Nishitsuji (ORCID: https://orcid.org/0000-0002-2872-1550)
- Masaya Sugiyama (ORCID: https://orcid.org/0000-0002-9084-7197)
- Takayuki Murata (ORCID: https://orcid.org/0000-0001-7228-0839)
- Kunitada Shimotohno
- Masashi Mizokami (ORCID: https://orcid.org/0000-0001-5269-4006)
Institutions
- Fujita Health University (JP)
- National Center for Global Health and Medicine (JP)
- Microbial Chemistry Research Foundation (JP)
- Kobe University (JP)
Publication Details
- Journal
- Hepatology
- Published
- 2025-01-23
- DOI
- https://doi.org/10.1097/hep.0000000000001239
- Citations
- 4
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 5.42
Funders
- Fujita Health University