Another cryo-EM success: structure of FXIII
In this issue of Blood, Singh et al report a 2.4- resolution cryogenic electron microscopy (cryo-EM) structure of coagulation factor XIII (FXIII). 1 The structure finally reveals the architecture of the A 2 B 2 heterotetrameric assembly, advances basic knowledge, and offers molecular context for the clinical manifestations of FXIII deficiency.
Authors
- Enrico Di (ORCID: https://orcid.org/0000-0003-2300-4891)
Institutions
- UCLouvain Saint-Louis Brussels (BE)
Publication Details
- Journal
- Blood
- Published
- 2025-01-23
- DOI
- https://doi.org/10.1182/blood.2024027405
- Primary Topic
- Characterization and Applications of Magnetic Nanoparticles
- Type
- article
- Field-Weighted Citation Impact
- 0.00