Another cryo-EM success: structure of FXIII

In this issue of Blood, Singh et al report a 2.4- resolution cryogenic electron microscopy (cryo-EM) structure of coagulation factor XIII (FXIII). 1 The structure finally reveals the architecture of the A 2 B 2 heterotetrameric assembly, advances basic knowledge, and offers molecular context for the clinical manifestations of FXIII deficiency.

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Publication Details

Journal
Blood
Published
2025-01-23
DOI
https://doi.org/10.1182/blood.2024027405
Primary Topic
Characterization and Applications of Magnetic Nanoparticles
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article
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article

Another cryo-EM success: structure of FXIII

Enrico Di
Blood
Characterization and Applications of Magnetic Nanoparticles
article

Another cryo-EM success: structure of FXIII

Enrico Di
article en

Abstract

In this issue of Blood, Singh et al report a 2.4- resolution cryogenic electron microscopy (cryo-EM) structure of coagulation factor XIII (FXIII). 1 The structure finally reveals the architecture of the A 2 B 2 heterotetrameric assembly, advances basic knowledge, and offers molecular context for the clinical manifestations of FXIII deficiency.

BloodVol. 145(4)
UCLouvain Saint-Louis Brussels (BE)
Openalex Percentile: Top 99%
Characterization and Applications of Magnetic Nanoparticles
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Another cryo-EM success: structure of FXIII — Enrico Di · Blood (2025) | TGRS Research Map | TGRS