Eye Movements and the Intraorbital Subarachnoid Space: Potential Contribution of Altered Cerebrospinal Fluid Pumping in Optic Neuropathies
Horizontal gaze and supraduction change subarachnoid CSF volume around the retrobulbar ON. Eye movements might thus pump CSF to promote ON health, but this effect is subnormal in adduction in POAG and NA-AION, suggesting that retrobulbar CSF pumping is associated with chronic forms of these optic neuropathies.
Authors
- Anthony C. Arnold (ORCID: https://orcid.org/0000-0002-9015-4542)
- Anne Louise Coleman (ORCID: https://orcid.org/0000-0002-0807-5176)
- Robert A. Clark (ORCID: https://orcid.org/0000-0002-2422-0337)
- Peter A. Quirós (ORCID: https://orcid.org/0000-0002-1133-9179)
- Laura Bonelli (ORCID: https://orcid.org/0000-0001-8819-3756)
- Joseph L. Demer (ORCID: https://orcid.org/0000-0001-9662-5352)
- Simon K. Law
- Kouros Nouri‐Mahdavi (ORCID: https://orcid.org/0000-0001-9403-8904)
- Joseph Caprioli (ORCID: https://orcid.org/0000-0002-2383-7263)
- Soh Youn Suh
- JoAnn A. Giaconi
Institutions
- University of California, Los Angeles (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-01-23
- DOI
- https://doi.org/10.1167/iovs.66.1.53
- Citations
- 2
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- Research to Prevent Blindness