Phenotypic and genotypic characterization of antimicrobial resistance and virulence profiles of <i>Salmonella enterica</i> serotypes isolated from necropsied horses in Kentucky

This study focuses on understanding how <i>Salmonella</i>, specifically isolated from horses, can resist antibiotics and cause disease. <i>Salmonella</i> is a well-known foodborne pathogen that can pose risks not only to animals but also to humans. By studying the bacteria from necropsied horses, the research aims to uncover how certain <i>Salmonella</i> strains develop resistance to antibiotics and which genetic factors make them more dangerous. In addition to antibiotic resistance, the research explores the biofilm-forming ability of these strains, which enhances their survival in harsh environments. The study also investigates their motility, a factor that contributes to the spread of infection. The findings can improve treatment strategies for horses and help prevent the transmission of resistant bacteria to other animals as well as humans. Ultimately, the research could contribute to better management of antibiotic resistance in both veterinary and public health contexts, helping to safeguard animal welfare and public health.

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Publication Details

Journal
Microbiology Spectrum
Published
2025-01-23
DOI
https://doi.org/10.1128/spectrum.02501-24
Citations
8
Primary Topic
Salmonella and Campylobacter epidemiology
Type
article
Field-Weighted Citation Impact
9.30

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article

Phenotypic and genotypic characterization of antimicrobial resistance and virulence profiles of Salmonella enterica serotypes isolated from necropsied horses in Kentucky

Erdal Erol, William G. Kelley, Catherine Glover, Yosra A. Helmy et al.
8 citations
Microbiology Spectrum
Salmonella and Campylobacter epidemiology
9.30
article

Phenotypic and genotypic characterization of antimicrobial resistance and virulence profiles of Salmonella enterica serotypes isolated from necropsied horses in Kentucky

Erdal Erol, William G. Kelley, Catherine Glover, Yosra A. Helmy, Ajran Kabir
article en
8 citations

Abstract

This study focuses on understanding how <i>Salmonella</i>, specifically isolated from horses, can resist antibiotics and cause disease. <i>Salmonella</i> is a well-known foodborne pathogen that can pose risks not only to animals but also to humans. By studying the bacteria from necropsied horses, the research aims to uncover how certain <i>Salmonella</i> strains develop resistance to antibiotics and which genetic factors make them more dangerous. In addition to antibiotic resistance, the research explores the biofilm-forming ability of these strains, which enhances their survival in harsh environments. The study also investigates their motility, a factor that contributes to the spread of infection. The findings can improve treatment strategies for horses and help prevent the transmission of resistant bacteria to other animals as well as humans. Ultimately, the research could contribute to better management of antibiotic resistance in both veterinary and public health contexts, helping to safeguard animal welfare and public health.

Microbiology SpectrumVol. 13(3)
University of Kentucky (US), Lincoln Memorial University (US), Martin University (US)
National Institutes of Health, National Center for Advancing Translational Sciences
Openalex Percentile: Top 2%
Salmonella and Campylobacter epidemiology
9.30
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Phenotypic and genotypic characterization of antimicrobial resistance and virulence profiles of <i>Salmonella enterica</i> serotypes isolated from necropsied horses in Kentucky — Erdal Erol, William G. Kelley, et al. · Microbiology Spectrum (2025) | TGRS Research Map | TGRS