Phenotypic and genotypic characterization of antimicrobial resistance and virulence profiles of <i>Salmonella enterica</i> serotypes isolated from necropsied horses in Kentucky
This study focuses on understanding how <i>Salmonella</i>, specifically isolated from horses, can resist antibiotics and cause disease. <i>Salmonella</i> is a well-known foodborne pathogen that can pose risks not only to animals but also to humans. By studying the bacteria from necropsied horses, the research aims to uncover how certain <i>Salmonella</i> strains develop resistance to antibiotics and which genetic factors make them more dangerous. In addition to antibiotic resistance, the research explores the biofilm-forming ability of these strains, which enhances their survival in harsh environments. The study also investigates their motility, a factor that contributes to the spread of infection. The findings can improve treatment strategies for horses and help prevent the transmission of resistant bacteria to other animals as well as humans. Ultimately, the research could contribute to better management of antibiotic resistance in both veterinary and public health contexts, helping to safeguard animal welfare and public health.
Authors
- Erdal Erol (ORCID: https://orcid.org/0000-0002-5130-1108)
- William G. Kelley
- Catherine Glover
- Yosra A. Helmy (ORCID: https://orcid.org/0000-0003-1470-5418)
- Ajran Kabir (ORCID: https://orcid.org/0000-0002-0145-3197)
Institutions
- University of Kentucky (US)
- Lincoln Memorial University (US)
- Martin University (US)
Publication Details
- Journal
- Microbiology Spectrum
- Published
- 2025-01-23
- DOI
- https://doi.org/10.1128/spectrum.02501-24
- Citations
- 8
- Primary Topic
- Salmonella and Campylobacter epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 9.30
Funders
- National Institutes of Health
- National Center for Advancing Translational Sciences