Identification of Key Genes and Pathways in Lenvatinib-resistant Hepatocellular Carcinoma using Bioinformatic Analysis and Experimental Validation
Diminished AHSG expression is strongly associated with lenvatinib resistance in HCC, suggesting that it may have implications for developing effective strategies to overcome this resistance.
Authors
- Zhaoyue Wang (ORCID: https://orcid.org/0000-0002-7989-7628)
- Jun Zhou (ORCID: https://orcid.org/0000-0002-6059-6251)
- Ming Yang (ORCID: https://orcid.org/0000-0001-5765-3844)
- Dongbing Li (ORCID: https://orcid.org/0000-0002-5227-9643)
- Ri-Ga Su
Institutions
- Peking University (CN)
- Peking University Cancer Hospital (CN)
- Beijing Tsinghua Chang Gung Hospital (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Current Medicinal Chemistry
- Published
- 2025-01-22
- DOI
- https://doi.org/10.2174/0109298673329991241111111941
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00