Elucidating the Causal Dynamics between Inflammatory Proteins and Atrial Fibrillation Risk Through Bidirectional Mendelian Randomization
This bidirectional MR study provides robust evidence for a causal relationship between specific inflammatory proteins and AF risk. The identified proteins could serve as potential biomarkers for AF risk stratification and targets for therapeutic intervention, offering new insights into the pathophysiology of AF and avenues for future research.
Authors
- Lanxi Xu (ORCID: https://orcid.org/0000-0003-2270-479X)
- Yuan Lv
- Xianjun Wu (ORCID: https://orcid.org/0000-0002-9637-7181)
- Bin Huang (ORCID: https://orcid.org/0000-0002-0305-7569)
Institutions
- Wenzhou Medical University (CN)
- Lishui University (CN)
- Lishui Central Hospital (CN)
- Lishui City People's Hospital (CN)
- Community Health Center (US)
Publication Details
- Journal
- Current Molecular Medicine
- Published
- 2025-01-22
- DOI
- https://doi.org/10.2174/0115665240347233250119190837
- Citations
- 1
- Primary Topic
- IL-33, ST2, and ILC Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.80