Integrated Transcriptome and Proteome Analyses Reveal Differentially Expressed Genes and Proteins in Granulosa Cells from Female Patients with Metabolic Syndrome-associated Infertility
The integrative analyses revealed significant molecular alterations in granulosa cells from MS patients with infertility. Identified DEGs, DEPs, and hub proteins suggested potential therapeutic targets and pathways for addressing MS-associated infertility.
Authors
- Yihong Guo (ORCID: https://orcid.org/0000-0003-3705-8065)
- Bo Sun (ORCID: https://orcid.org/0000-0002-5548-3850)
- Fang Wang (ORCID: https://orcid.org/0009-0008-5160-7909)
- Wenbin Niu (ORCID: https://orcid.org/0000-0001-5507-1592)
- Wanjun Zhang (ORCID: https://orcid.org/0000-0003-2725-3182)
- Jun Zhai (ORCID: https://orcid.org/0000-0001-9566-865X)
- Fangli Dong
Institutions
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Current Medicinal Chemistry
- Published
- 2025-01-22
- DOI
- https://doi.org/10.2174/0109298673357582241223070335
- Citations
- 1
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.70