Nutritional Evaluation and Free Radical Scavenging Activity of Nano-formulated Selenium-Moringa Peregrine Seed Extract as a Promising Suppressor of TGF-β1/P38/NF-kβ Signaling Pathway in HgCl <sub>2</sub> Intoxicated-mice

The study reveals that Moringa peregrina extract combined with selenium nanoparticles (MPESeNPs) offers significant protection against oxidative damage induced by HgCl₂ exposure. The enhanced antioxidant and anti-inflammatory properties of MPE-SeNPs, particularly at a dose of 38.65 mg/kg body weight, demonstrate their potential as a powerful natural therapy for pulmonary fibrosis. These findings underscore the promise of MPE-SeNPs in improving lung health by mitigating oxidative stress, reducing inflammation, and promoting tissue repair, paving the way for innovative treatments in respiratory medicine.

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Publication Details

Journal
Current Pharmaceutical Biotechnology
Published
2025-01-22
DOI
https://doi.org/10.2174/0113892010352642241221152820
Primary Topic
Moringa oleifera research and applications
Type
article
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article

Nutritional Evaluation and Free Radical Scavenging Activity of Nano-formulated Selenium-Moringa Peregrine Seed Extract as a Promising Suppressor of TGF-β1/P38/NF-kβ Signaling Pathway in HgCl 2 Intoxicated-mice

Samar Aborhyem, Mohammed A. Hussein, Mahmoud El-Tawila, Reham A. Hamdy
Current Pharmaceutical Biotechnology
Moringa oleifera research and applications
article

Nutritional Evaluation and Free Radical Scavenging Activity of Nano-formulated Selenium-Moringa Peregrine Seed Extract as a Promising Suppressor of TGF-β1/P38/NF-kβ Signaling Pathway in HgCl 2 Intoxicated-mice

Samar Aborhyem, Mohammed A. Hussein, Mahmoud El-Tawila, Reham A. Hamdy
article en

Abstract

The study reveals that Moringa peregrina extract combined with selenium nanoparticles (MPESeNPs) offers significant protection against oxidative damage induced by HgCl₂ exposure. The enhanced antioxidant and anti-inflammatory properties of MPE-SeNPs, particularly at a dose of 38.65 mg/kg body weight, demonstrate their potential as a powerful natural therapy for pulmonary fibrosis. These findings underscore the promise of MPE-SeNPs in improving lung health by mitigating oxidative stress, reducing inflammation, and promoting tissue repair, paving the way for innovative treatments in respiratory medicine.

Current Pharmaceutical BiotechnologyVol. 27(3)
October 6 University (EG), Alexandria University (EG)
Zero hunger
Openalex Percentile: Top 99%
Moringa oleifera research and applications
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